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ANGELIQ is available in two strengths
Talk with your healthcare provider about which ANGELIQ strength may be right for you.
Guidelines published by the North American Menopause Society (NAMS)—the leading scientific nonprofit organization devoted to promoting women's health during menopause—recommend that doctors reassess your hormone treatment on an ongoing basis to be sure that you are getting the lowest effective dose of estrogen based on your treatment goals and your individual risk.
You and your healthcare provider should talk regularly (for example, every 3-6 months) about whether you still need treatment with ANGELIQ. Take advantage of the opportunity to discuss the changes you're experiencing, along with your overall health. If you're taking hormone therapy (HT), use these visits to review your treatment plan and ask any questions about HT and any other medications you may be taking.
If you have any change in the frequency or severity of your symptoms, be sure to let your healthcare provider know. You may need to have your dose adjusted, or be ready to try stopping hormone treatment to see if symptoms return.
Staying healthy through menopause and beyond
As you move through menopause and beyond, paying attention to your health can play an important role in your well-being. Here are a few ideas:
- Try simple steps such as eating a balanced diet and getting regular exercise. Natural stress reducers like yoga or meditation can help you feel better and benefit your health overall. Before starting a new exercise program, talk with your healthcare provider about what types of exercise may be best for you
- Get a mammogram. As you age, your risk for breast cancer rises. Mammography (mammogram) is the most common screening method for detecting abnormalities in the breast. It’s recommended that you have a mammogram (breast x-ray) every year unless your healthcare provider sets a different schedule. If members of your family have had breast cancer or if you have ever had lumps or an abnormal mammogram, you may need to have breast exams more often
- Get other checks your healthcare provider recommends, such as an annual Pap smear, to help detect potential cancers. The sooner problems are detected, the sooner they can be treated
Consider making changes
(Always check with your healthcare provider before changing your exercise regimen.)
- Create balance. Emotional health may require making a conscious effort to balance the obligations of work and caring for others with the need to look after yourself. It's important to take time for yourself, talk with friends, do the activities you enjoy, and maintain a healthy sense of humor
- Exercise regularly. Regular exercise may help with mood swings, weight gain, and general health. For healthy bones, aim to do weight-bearing forms of exercise such as walking, jogging, or dancing 3 times a week
- Eat a healthy diet. Make a point of choosing foods that are low in fat, high in fiber and rich in calcium. Reach for healthy alternatives such as fruit, vegetables, whole-grain breads and cereals, beans, soy foods and fat-free dairy foods
What are the most serious risks of taking ANGELIQ?
ANGELIQ may increase the risk of heart attack; stroke; blood clots; dementia; cancer of the breast, ovary, or lining of the uterus (womb); high blood pressure; high blood sugar; gallbladder disease; liver problems; or enlargement of benign tumors of the uterus (fibroids).
In addition, ANGELIQ contains drospirenone which may increase the potassium level in your blood. Do not take ANGELIQ if you have kidney, liver or adrenal disease because these conditions may also increase the potassium level in your blood. Tell your healthcare provider about all the medicines you take because some other medicines may increase potassium. In some situations, your healthcare provider may recommend testing your blood for potassium level.
Call your healthcare provider right away if you have:
- New breast lumps; changes in vision or speech; sudden new severe headaches; severe pain in your chest or legs with or without shortness of breath, weakness and fatigue; vaginal bleeding while taking ANGELIQ
IMPORTANT SAFETY INFORMATION
What is ANGELIQ® used for?
ANGELIQ (0.25 mg drsp/0.5 mg estradiol E2) tablets and ANGELIQ (0.5 mg drsp/1.0 mg E2) tablets are used after menopause in women who have a uterus to reduce moderate to severe hot flashes.
In addition, ANGELIQ (0.5 mg drsp/1.0 mg E2) is used after menopause in women who have a uterus to treat moderate to severe dryness, itching, and burning in or around the vagina. If you use ANGELIQ (0.5 mg drsp/1.0 mg E2) only to treat dryness, itching, and burning in or around your vagina, talk with your healthcare provider about whether a topical vaginal product would be better for you.
What is the most important information I should know about ANGELIQ (combination of estrogen and progestin hormones)?
- Do not use estrogens with progestins, or estrogen-alone, to prevent heart disease, heart attacks, strokes, or dementia (decline of brain function)
- Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
- Using estrogens with progestins, or estrogen-alone, may increase your chance of getting dementia, based on a study of women 65 years of age or older
- Using estrogen-alone may increase your chance of getting strokes, blood clots or cancer of the uterus (womb)
- You and your healthcare provider should talk regularly about whether you still need treatment with ANGELIQ
Who should not use ANGELIQ?
Do not use ANGELIQ if you have had your uterus removed (hysterectomy). ANGELIQ contains a progestin to decrease the chances of getting cancer of the uterus. If you do not have a uterus, you do not need a progestin and you should not use ANGELIQ.
Do not start taking ANGELIQ if you have unusual vaginal bleeding; currently have or have had certain cancers, such as cancer of the breast or uterus; had a stroke or heart attack in the past year; currently have or have had blood clots; have kidney disease, liver disease, or disease of your adrenal glands; have been diagnosed with a bleeding disorder; are allergic to ANGELIQ or any of its ingredients; or are pregnant or plan to become pregnant.
What are the most serious risks of taking ANGELIQ?
ANGELIQ may increase the risk of heart attack; stroke; blood clots; dementia; cancer of the breast, ovary, or lining of the uterus (womb); high blood pressure; high blood sugar; gallbladder disease; liver problems; or enlargement of benign tumors of the uterus (fibroids).
In addition, ANGELIQ contains drospirenone which may increase the potassium level in your blood. Do not take ANGELIQ if you have kidney, liver or adrenal disease because these conditions may also increase the potassium level in your blood. Tell your healthcare provider about all the medicines you take because some other medicines may increase potassium. In some situations, your healthcare provider may recommend testing your blood for potassium level.
Call your healthcare provider right away if you have:
- New breast lumps; changes in vision or speech; sudden new severe headaches; severe pain in your chest or legs with or without shortness of breath, weakness and fatigue; vaginal bleeding while taking ANGELIQ
What are the most common side effects in ANGELIQ clinical trials?
The most common side effects were stomach and abdominal pain, vaginal bleeding or spotting, breast pain/discomfort, headache, vaginal yeast infection, nausea, diarrhea, and fluid retention.
ANGELIQ is available by prescription only.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
For important risk and use information about ANGELIQ, please see the full Prescribing Information.
